How a man and his dogs discovered the cause of narcolepsy

Loading player...
The Breakthrough prizes are described by their Silicon Valley founders as ‘the Oscars of science’, and while they are not as glamorous, they do come with a $3m award. This year, one of the prizes was dished out to Prof Emmanuel Mignot at Stanford University and Masashi Yanagisawa at the University of Tsukuba for their work uncovering the cause of narcolepsy. Their discovery has opened the door to the development of treatments for this chronic and often debilitating condition. Madeleine Finlay speaks to Mignot about how he pinpointed the cause of narcolepsy, why it is similar to diabetes and what sleep mysteries he wants to solve next. Help support our independent journalism at theguardian.com/sciencepod
27 Sep 2022 English United Kingdom Science · Nature

Other recent episodes

‘The undruggable became druggable’: a breakthrough cancer treatment

A daily pill can double survival time in patients with the world’s deadliest cancer, according to the results of a clinical trial that experts are saying is a gamechanger and one of the biggest breakthroughs in decades. To find out more about how daraxonrasib works and how life-changing it could…
11 Jun 14 min

The dinosaurs who survived the asteroid

While many dinosaurs were wiped out when a colossal asteroid struck Earth 66m years ago, one group survived: birds. Prof Steve Brusatte, a palaeontologist at the University of Edinburgh, has written a new book, The Story of Birds, tracing the evolution of our feathered friends from their dinosaur origins. He…
9 Jun 17 min

The incredible science of the sleeping brain

Humans have been wondering why we sleep for thousands of years. Is sleep’s purpose rest and relaxation, memory consolidation or maybe cognitive processing? In the last 15 years, scientists have discovered another possible explanation – waste disposal. In 2012 neuroscientist Maiken Nedergaard’s lab discovered that the brain has its own…
2 Jun 14 min

Are robots nearing their ChatGPT moment?

Last month at Beijing’s half marathon, a robot named Lightning beat the human world record by nearly seven minutes. It’s the latest in a string of AI-powered milestones that have got people wondering whether robots are about to enter our everyday lives, just as chatbots have. And the country leading…
28 May 17 min